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1.	Efe, C, et al. (author) Effects of immunosuppressive drugs on COVID-19 severity in patients with autoimmune hepatitis 2022 In: Liver international : official journal of the International Association for the Study of the Liver. - : Wiley. - 1478-3231. ; 42:3, s. 607-614 Journal article (peer-reviewed)
2.	Efe, C., et al. (author) Validation of Risk Scoring Systems in Ursodeoxycholic Acid-Treated Patients With Primary Biliary Cholangitis 2019 In: American Journal of Gastroenterology. - : Ovid Technologies (Wolters Kluwer Health). - 0002-9270 .- 1572-0241. ; 114:7, s. 1101-1108 Journal article (peer-reviewed)abstract INTRODUCTION: Risk stratification based on biochemical variables is a useful tool for monitoring ursodeoxycholic acid (UDCA)-treated patients with primary biliary cholangitis (PBC). Several UDCA response criteria and scoring systems have been proposed for risk prediction in PBC, but these have not been validated in large external cohorts. METHODS: We performed a study on data of 1746 UDCA-treated patients with PBC from 25 centers in Europe, United States, and Canada. The prognostic performance of the risk scoring systems (GLOBE and UK-PBC) and the UDCA response criteria (Barcelona, Paris I, Paris II, Rotterdam, and Toronto) were evaluated. We regarded cirrhosis-related complications (ascites, variceal bleeding, and/or hepatic encephalopathy) as clinical end points. RESULTS: A total of 171 patients reached a clinical end point during a median 7 years (range 1-16 years) of follow-up. The 5-, 10- and 15-year adverse outcome-free survivals were 95%, 85%, and 77%. The GLOBE and UK-PBC scores predicted cirrhosis-related complications better than the UDCA response criteria. The hazard ratio (HR) for a 1 standard deviation increase was HR 5.05 (95% confidence interval (CI): 4.43-5.74, P < 0.001) for the GLOBE score and HR 3.39 (95% CI: 3.10-3.72, P < 0.001) for the UK-PBC score. Overall, the GLOBE and UK-PBC risk scores showed similar and excellent prognostic performance (C-statistic, 0.93; 95% CI: 0.91%-95% vs 0.94; 95% CI: 0.91%-0.96%). DISCUSSION: In our international, multicenter PBC cohort, the GLOBE and UK-PBC risk scoring systems were good predictors of future cirrhosis-related complications.
3.	Efe, C, et al. (author) SARS-CoV-2 vaccination and risk of severe COVID-19 outcomes in patients with autoimmune hepatitis 2022 In: Journal of autoimmunity. - : Elsevier BV. - 1095-9157 .- 0896-8411. ; 132, s. 102906- Journal article (peer-reviewed)

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Type of publication: journal article (3)

Type of content: peer-reviewed (3)

Author/Editor: Wahlin, S. (3)Undo refine; Efe, C (3); Lytvyak, E (3); Tascilar, K (3); Silva, M. (2); Mendizabal, M. (2); show more...; Invernizzi, P (2); Aguirre, J (2); Montano-Loza, AJ (2); Purnak, T (2); Ridruejo, E (2); Idilman, R (2); De Martin, E (2); Cristoferi, L (2); Demir, N. (2); Lammert, C (2); Dhanasekaran, R (2); Fischer, J. (1); Nilsson, Emma (1); Levy, C. (1); Marschall, Hanns-Ulr ... (1); Schiano, T (1); Rorsman, Fredrik, Do ... (1); Werner, Mårten (1); Bjornsson, E (1); Floreani, A (1); Aydın, M. (1); Cengiz, M (1); Önnerhag, Kristina (1); Berg, T. (1); Yildirim, S (1); Fagiuoli, S (1); Vincent, M (1); Ozaslan, E (1); Hernandez, N (1); Assis, DN (1); Muratori, L (1); Semela, D. (1); Garcia, SR (1); Urzua, A (1); Satapathy, SK (1); Silveira, M. (1); Ekin, N (1); Anders, M (1); Eliasson, J (1); Yoshida, E (1); Kahramanoglu-Aksoy, ... (1); Muratori, P (1); Yoshida, EM (1); Schiano, TD (1); show less...

University: Karolinska Institutet (3); University of Gothenburg (1); Umeå University (1); Uppsala University (1); Örebro University (1); Lund University (1)Undo refine

Language: English (3)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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